Gastrointestinal Tract, Women’s Health, Anti-inflammatories, Arthritis
Celebrex has analgesic, antipyretic and also anti-inflammatory effect. In the experiments, on animals has shown effectiveness in reducing the incidence of cancer of the colon.
Celebrex does not violate the natural processes caused by prostaglandins class E1 in platelets, the intestines and the stomach.
In the application of Celebrex frequency education gastroduodenal ulcers and complications associated with them, significantly lower than the application of other similar drugs such as acetylsalicylic acid, naproxen, ibuprofen, that confirmed the results of endoscopic examinations. The difference in the development of ulcers is statistically significant.
In studies in healthy volunteers, it has been proven that the use of Celebrex 200mg at a dosage of 1.2 g in day, Celebrex has no effect on the function of platelets and indicators of blood coagulation.
In studies of Celebrex 200mg caused increase in a risk of sudden cardiovascular death and thrombosis, including in vital organs, compared with placebo, but this difference was not statistically significant. Celebrex 200mg increases a risk of nonfatal heart attacks, reduces a risk of nonfatal stroke and has no effect on cardiovascular mortality. When adding aspirin to therapy, these results did not change.
Buy Celebrex, which is well absorbed from the digestive tract, reaching a maximum concentration in 2-3 hours. Eating, especially oily, delays the absorption of Celebrex 200, with the maximum concentration can be achieved through 6-7 hours, which is by 4 hours longer, compared with the reception on an empty stomach.
In patients with low body weight, concentration in the blood Celebrex above, as well as more high concentrations of note in women, compared to men, so women with small weight (up to 50 kg) should start the treatment with a minimum of therapeutic doses, especially for elderly patients.
Increase of concentration is observed and in persons of a Negroid race, it’s necessary to start treatment with the minimum therapeutic dosages.
If any of the liver light degree, dosage adjustment isn’t required in the case of moderate degree requires a reduction in dosage by 50%.
In violation of the kidney correction of dosage is not required, as with the urine is only about 1% of the preparation.
The studies were registered temporarily reduce the excretion of sodium and, respectively, fluid retention, with the development of peripheral edema. Nevertheless, the increase in cases of arterial hypertension was not, and the swelling went without treatment.
Various reviews of Celebrex allow it to you the opinion of the effectiveness of the drug.
Indications to application:
As a symptomatic therapy at:
- - arthritis (rheumatoid arthritis, osteoarthritis), spondylitis;
- - algodismenorrhea;
- - acute pain.
Celebrex take in the composition of complex therapy of patients with family adenomatous polyposis to reduce the number and size of adenomatous colorectal polyps.
Method of application:
- It is recommended to visit Celebrex in dose of two hundred mg twice a day.
- Given that the complications of the cardiovascular system dependent on the dose of the preparation should be used drug in minimum effective dosage, courses of small duration.
Buy Celebrex and use in osteoarthritis:
recommended daily dose of Celebrex 200mg, reception is possible, as Celebrex 200mg once a day, and on the Celebrex 100 mg twice a day. If necessary, the dosage can be increased up to 800 mg in day (400mg twice a day), without increasing the risk of side effects.
Buy Celebrex and use in rheumatoid arthritis:
recommended daily I dosage of 200 to 400 mg per day in 2 admission. If necessary, the dose can be increased up to 800 mg / day (400 mg twice a day), without increasing the risk of by-effects.
Buy Celebrex online and use the ankylosing spondylitis:
recommended daily I dose of 200 mg, reception is possible, as 200mg once a day, and on the 100 mg twice a day. If necessary, it is possible to use in the dose of four hundred mg a day.
Buy Celebrex online and use in acute pain:
Initial dose of Celebrex is 400-600 mg per day, further on 200 mg twice per day.
Application in the family adenomatous polyposis:
Celebrex is prescribed as an additional means, to the standard therapy. The recommended of Celebrex dose is 400 mg twice a day.
For patients older dose adjustment is required, except in cases when their body weight does not exceed 50 kg.
In the application of Celebrex in patients with moderate degree of reduced function of the liver, recommended by decreasing the daily dosage of 2 times. Patients with heavy hepatic insufficiency have no experience of use of a preparation.
- In renal insufficiency, light and middle severity, the reduction in dose is not required. Patients with heavy nephritic insufficiency have no experience of application of Celebrex.
- If you used Celebrex preparation, be not too lazy to leave the review of medicine application. The article tells briefly about what is Celebrex. For complete information, refer to the doctor.